Sometimes, maybe for no reason at all, you might become agitated with a feeling of restless agitation. This feeling is a sense ofdisquietude, an edgy feeling that something in your universe is out of order.
If you break down the word disquietude you come to its root word, quiet, which means still or noiseless. The dis- prefix means “not,” giving it the opposite meaning, and the ending -tude makes it a state of being. So the word literally means “state of being unquiet.” For example, it was said in the Washington Post that the 19th-20th-century artist Edward Hopper’s paintings present a picture of the disquietude, or uneasiness, of American life.